3-Azetidinol, 1-(phenylmethyl)- - Names and Identifiers
3-Azetidinol, 1-(phenylmethyl)- - Physico-chemical Properties
Molecular Formula | C10H13NO
|
Molar Mass | 163.22 |
Density | 1.188±0.06 g/cm3(Predicted) |
Melting Point | 64-65 °C |
Boling Point | 259.2±33.0 °C(Predicted) |
Flash Point | 105.864°C |
Vapor Presure | 0.007mmHg at 25°C |
pKa | 14.33±0.20(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Sensitive | Air Sensitive |
Refractive Index | 1.619 |
MDL | MFCD00963607 |
3-Azetidinol, 1-(phenylmethyl)- - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
HS Code | 29339900 |
3-Azetidinol, 1-(phenylmethyl)- - Introduction
1-benzylazetidin-3-ol(1-benzylazetidin-3-ol), also known as benzylazetidin-3-ol, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 1-benzylazetidin-3-ol is a colorless to light yellow liquid at room temperature, and it can also be in solid form.
-Solubility: Its solubility in water is low, and it has good solubility in organic solvents such as ethanol and dimethylformamide.
-Stability: It can exist stably under conventional storage conditions, and is stable under most conventional chemical reaction conditions.
Uses: 1-benzylazetidin-3-ol has some applications and uses in the chemical field, such:
-It can be used as a starting material for drug synthesis or drug intermediates, and used to synthesize some biologically active compounds.
-It can also be used as a catalyst or one of the ligands in the catalytic reaction process in organic synthesis.
Preparation Method: A common method for preparing 1-benzylazetidin-3-ol is by reacting 1-benzylchloroacetone with NH4OH in the presence of sodium hydroxide at a suitable temperature. The specific steps may be: first, reacting 1-benzylchloroacetone with aqueous ammonia in a suitable solvent to generate 1-benzyl-3-aminoacetone, and then performing a reduction reaction to reduce the aminoacetone to 1-benzylazetidin-3-ol.
Safety information: There is currently no specific public safety data report on the safety information of 1-benzylazetidin-3-ol. However, as an organic compound, it should generally comply with chemical and laboratory safety procedures, avoid direct contact with skin, inhalation of gases or dust, and maintain its correct storage and handling methods. It is best to conduct a safety assessment before use and wear personal protective equipment such as gloves, goggles and protective clothing during operation. If possible, the safety data sheet of the chemical substance should be read for more safety-related information before use.
Last Update:2024-04-09 21:32:42